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These PET scan images provided by the New England Journal of Medicine in January 2024 show a reduction in amyloid-beta levels in an Alzheimer's patient after focused ultrasound treatment to open the blood-brain barrier after 26 weeks. Red is associated with higher levels of amyloid-beta levels. Scientists have found a way to help Alzheimer’s drugs seep inside the brain faster — by temporarily breaching its protective shield.

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Study: Ultrasound tool may aid Alzheimer's drugs absorption
January 10, 2024 1 a.m.

Study: Ultrasound tool may aid Alzheimer's drugs absorption

Scientists have found a way to help Alzheimer's drugs seep inside the brain faster — using sound waves to jiggle a temporary opening in its protective shield. Some new drugs modestly slow Alzheimer's worsening by attacking brain-clogging amyloid plaque, with doses every few weeks for well over a year. In a novel experiment, West Virginia University researchers added the ultrasound tool to three patients' drug doses for six months. In spots in the brain where that shield was opened, more plaque was cleared. The findings were published Wednesday in the New England Journal of Medicine.